Simple Spicy Salsa Meatloaf

Make a salsa meatloaf that matches your heat tolerance…

We love this simple salsa meatloaf recipe because you can adjust it to how much spice you really want! Throwing a party with a ton of spicy food lovers? Use a habanero pepper salsa as the base. Having a family dinner where a little spice is ok, but not too much? Opt for a mild salsa that everyone can enjoy. Want it a little sweet? Opt for a fruit-based salsa. It’s that simple. You can even match the guacamole heat to match!

Best of all, like many meatloaves, this is a “mix it up and bake it” type recipe. You don’t need to be an aspiring chef to pull this meal together. You need just a few basic ingredients, an oven, and an hour. There’s a serious amount of flavor in this salsa meatloaf for how little prep and time you need. For those lacking kitchen skills, it’s a great way to impress family and friends.

If salsa meatloaf is right up your alley, give our Cajun meatloaf a try as well. It features a trio of Southern flavor: Cajun seasoning, Tabasco sauce, and cayenne pepper. It’s a bold meatloaf with something to say – perfect for fans of Louisiana cuisine and bold spices.

Simple spicy salsa meatloaf_1

Simple Spicy Salsa Meatloaf

Simple to make, but packed full of flavor
5 from 1 vote
Prep Time 15 minutes
Cook Time 1 hour
Total Time 1 hour 15 minutes
Course Meal
Servings 8 servings
Calories 222 kcal


  • 2 pounds lean ground beef
  • 1 jar salsa 15 ounces, choose your heat
  • 1 white onion diced, medium-sized
  • 1 cup bread crumbs
  • 1 egg beaten
  • 1 teaspoon salt
  • 1/2 teaspoon cayenne pepper
  • Guacamole on the side


  • Preheat oven to 350° Fahrenheit
  • Combine all ingredients into a large bowl and mix thoroughly.
  • Move the mix into a meatloaf pan and spread evenly throughout the pan.
  • Place the pan into the oven and bake the meatloaf approximately one hour (until the top has turned brown).
  • Pull from oven and let the meatloaf rest for 5 minutes prior to cutting.
  • Serve with guacamole on the side.


Calories: 222kcalCarbohydrates: 11gProtein: 27gFat: 7gSaturated Fat: 3gCholesterol: 91mgSodium: 474mgPotassium: 446mgFiber: 1gSugar: 1gVitamin A: 80IUVitamin C: 1mgCalcium: 41mgIron: 3.5mg
Keyword Cayenne Pepper, Salsa
Did you make this?Mention @PepperScale or tag #PepperScale so we can see what you made!

UPDATE NOTICE: This post was updated on March 19, 2022 to include new content.
5 from 1 vote
Notify of

1 Comment
Inline Feedbacks
View all comments
Paul Brown

5 stars
I tasked the hubby with throwing this in the crockpot the other day for dinner. It turned out so good! I wouldn’t change a thing. I also shared it on my blog today — linking back to you of course 🙂 Thanks for sharing.